Dr. Klein is a graduate of Des Moines University College of Osteopathic Medicine in Des Moines, Iowa. He completed an internship through the Ohio University College of Osteopathic Medicine in Toledo, Ohio. His internal medicine residency was at the University of Minnesota and he completed fellowships in both Cardiology and Interventional Cardiology at the University of Cincinnati. Dr. Klein was Chief Cardiology fellow in 2007 and 2008, and was recognized with an Outstanding Cardiology Fellow's Award in 2008. He is a fellow of the American College of Cardiology and is board certified in internal medicine, interventional cardiology, cardiovascular disease and nuclear cardiology.

As an interventional cardiologist, Dr. Klein specializes in performing diagnostic and interventional coronary, renal and peripheral procedures, including percutaneous closure of atrial septal defects (ASDs). Special interest includes treatment of Peripheral Arterial Disease. Dr. Klein also specializes in echocardiography, transesophageal echocardiography, nuclear cardiology and cardiac CT angiography.

Dr. Klein's primary office locations are Largo and Clearwater.